Clinical Observation of Flurbiprofen Axetil Combined with Propofol in Induced Abortions

OBJECTIVE:To investigate the anesthetic effect and safety of flurbiprofen axetil combined with propofol on the induced abortion.METHODS:2 000 patients undergoing induced abortion were randomly divided into flurbiprofen axetil combined with propofol group(observation group)and propofol group(control group)with 1 000 patients in each group.Observation group was administrated with flurbiprofen axetil 50 mg intravenously first and 10 minutes later followed with propofol 2.5 mg.kg-1.Control group was administrated with 2.5 mg.kg-1 propofol.BP,HR and SpO 2 were recorded before anaesthesia and at the beginning of surgery.Onset time,recovery time,operation time,amount of propofol,intraoperative bleeding volume,anesthetic efficacy,case number of excitement and dysphoria after awakening,postoperative uterine contraction pain score,adverse drug reaction and the degree of satisfaction score were recorded.RESULTS:There was no significant difference in intraoperative bleeding volume between 2 groups(P0.05).Anesthetic efficacy of observation group was significantly better than that of control group,and consumption amount of propofol in observation group was lower than in control group.Recovery time of observation group was shorter than that of control group,there was statistical significance(P0.01).The incidence of dysphoria after awakening in observation group was lower than in control group,and postoperative VAS score were significantly lower than in control group.The score of satisfaction degree was significantly higher in observation group than in control group,there was statistical significance(P0.01).CONCLUSION:Flurbiprofen axetil combined with propofol is effective for anaesthesia of induced abortion.It is a safe and effective scheme because of controlling intraoperative bleeding volume and obtaining sound satisfaction degree.