Treatment of Liver Cancer with Portal Vein Tumor Thrombus with TACE plus Percutaneous Portal Vein Injection of Ethanol Combined Lipiodol

Objective To study the effect of treatment with transcatheter artery chemoembolization(TACE) plus percutaneous portal vein injection of ethanol combined lipiodol on liver cancer with portal vein tumor thrombus(PVTT).Methods 25 cases liver cancer patients were treated by injection of ethanol combined lipiodol into liver cancer with portal vein tumor thrombus after 5~7 days of TACE.Results The rates of PVTT disappearance and shrinkage were 24%(6/25) and 48%((12/25)) respectively.The tumor mass shrinkage rates was 88%(22/25) and AFP negative reversion rates was 80%.The emergence time of portal vein was put off after treatment.Two groups of cases is apparently different before and after treatment(P0.05).The 1,2 and 3 year survival rates for combined interventional therapy were 76%(19/25)、40%(10/25)and 24%(6/25).Conclusion Combined interventional therapy is a very effective way for liver cancer with portal vein tumor thrombus.