Effect of CMHS,MOS and Flavomycin on Antioxidant Status and Blood Biochemical Parameters of Laying Chicks

Two hundred and ninety-four 1 day-old laying chicks were used in the study to investigate effects of 4 Chinese medical herbs (CMHS): Ligustrum Lucidum (LL), Schisandra Chinensis (SC), Si Jun Zi Tiang (SJZT) and Liu Wei Di Huang Wan (LWDHW), Mannanoligosaccharides (MOS) and Flavomycin on antioxidant status and blood biochemical parameters of laying chicks. Experiment birds were divided into 7 groups. Group 1, 2, 3, 4 were fed a basal diet supplemented with 1% LL, SC, SJZT or LWDHW, respectively.Group 5 were fed the basal diet supplemented with 50 mg/kg MOS. Group 6 were fed the basal diet supplemented with 5 mg/kg flavomycin. Group 7 were fed the basal diet.The results showed that SC and LWDHW enhanced serum superoxide dismutase (SOD) activity significantly,at the same time, LL enhanced heart SOD activity significantly, compared with the control group. No significant differences were observed on both liver and kidney SOD activity. Meanwhile, LL and SC increased serum glutathione reductase (GR) activity (P0.05) significantly, and SJZT significantly increased heart and liver GR activity (P0.05), contrast to control group. But little influence was observed on kidney GR activity. LL greatly decreased serum malondialdehyde (MDA) concentration, and LL and SJZT significantly decreased heart MDA concentration, compared with control group. Otherwise, no significant difference was observed on both liver and kidney MDA concentration. It was also showed that these feed additives have little influence on blood biochemical parameters of laying chicks. In conclusion, LL, SC and SJZT exhibited better antioxidant effect than others. Whereas, all of these feed additives have little influence on blood biochemical of laying chicks.