Effects of atorvastatin on C-reactive protein in old patients with carotid atherosclerosis and hypertension

Aim To observe the effeets of atorvastatin on C-reactive protein in old patients with carotid atherosclerosis and hypertension.Methods 78 patients were divided randomly into two groups:atorvastatin intervention group(n=38) and normal intervention group(n=40).After treatment for 3 months carotid Doppler ultrasonography was carried out.Results After treatment for 3 months,the levels of blood lipid and CRP in intervention groups were lower than that in control group(P0.05).And the carotid atherosclerotic plaque size and vulnerable plaque rate reduced in atorvastatin intervention groups(P0.05).Conclusion Atorvastatin had preventive effect on stabilizing atherosclerotic plaques,and could reduce the CRP level and lipid in patients with carotid atherosclerosis.