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The relationship between blood homocysteine and coronary atherosclerotic heart disease

YU Hanli

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Abstract

Objective:To study the relationship between the incidence,the development,the therapy,and the prognosis of coronary atherosclerotic heart disease (CHD) and plasma homocysteine (HCY).Methods: Highperformance liquid chromatography with fluorescence detection had been utilized for the rapid determination of total HCY in serum.Thirty subjects were studied,20 of them had CHD,and the others were healthy controls.Results:The mean HCY from CHD and control group were (16 50±7 90) μmol/L and (7 52±4 00)μmol/L,respectively.The difference was significant ( P 0 01).Conclusions:Hyperhomocysteinemia is an independent risk factor for CHD.

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What this paper is about

Objective:To study the relationship between the incidence,the development,the therapy,and the prognosis of coronary atherosclerotic heart disease (CHD) and plasma homocysteine (HCY).Methods: Highperformance liquid chromatography with fluorescence detection had been utilized for the rapid determination of total HCY in serum.Thirty subjects were studied,20 of them had CHD,and the others were healthy controls.Results:The mean HCY from CHD and control group were (16 50±7 90) μmol/L and (7 52±4 00)μmol/L,respectively.The difference was significant ( P 0 01).Conclusions:Hyperhomocysteinemia is an independent risk factor for CHD.

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Available abstract

Objective:To study the relationship between the incidence,the development,the therapy,and the prognosis of coronary atherosclerotic heart disease (CHD) and plasma homocysteine (HCY).Methods: Highperformance liquid chromatography with fluorescence detection had been utilized for the rapid determination of total HCY in serum.Thirty subjects were studied,20 of them had CHD,and the others were healthy controls.Results:The mean HCY from CHD and control group were (16 50±7 90) μmol/L and (7 52±4 00)μmol/L,respectively.The difference was significant ( P 0 01).Conclusions:Hyperhomocysteinemia is an independent risk factor for CHD.

Key concepts: Medicine, Hyperhomocysteinemia, Homocysteine, Internal medicine, Coronary heart disease, Plasma homocysteine, Cardiology, Incidence (geometry)

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