2012Pharmacy TodayRequires access

Verification Study for 3T3 Neutral Red Uptake Phototoxicity Test

Li Junpeng

Open publisher page 0 citations

Abstract

Objective To verify the feasibility of application of 3T3 neutral Red uptake in phototoxicity.Methods Two kinds of unknown chemical were dispensed into the culture media of Balb/c 3T3 cells.Then the viability of Balb/c 3T3 cells was assessed by neutral red uptake test.Results A positive result was obtained with sample 1,while a negative result was obtained with sample 2.Conclusion It is suggested that in vitro 3T3 neutral Red uptake test can be used to assess the phototoxic effects of chemical.

About this research paper

What this paper is about

Objective To verify the feasibility of application of 3T3 neutral Red uptake in phototoxicity.Methods Two kinds of unknown chemical were dispensed into the culture media of Balb/c 3T3 cells.Then the viability of Balb/c 3T3 cells was assessed by neutral red uptake test.Results A positive result was obtained with sample 1,while a negative result was obtained with sample 2.Conclusion It is suggested that in vitro 3T3 neutral Red uptake test can be used to assess the phototoxic effects of chemical.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To verify the feasibility of application of 3T3 neutral Red uptake in phototoxicity.Methods Two kinds of unknown chemical were dispensed into the culture media of Balb/c 3T3 cells.Then the viability of Balb/c 3T3 cells was assessed by neutral red uptake test.Results A positive result was obtained with sample 1,while a negative result was obtained with sample 2.Conclusion It is suggested that in vitro 3T3 neutral Red uptake test can be used to assess the phototoxic effects of chemical.

Key concepts: Phototoxicity, Neutral red, In vitro, 3T3 cells, Chemistry, Biochemistry, Cytotoxicity, Gene

Related papers

Back to paper searchBrowse research topicsOriginal source
Verification Study for 3T3 Neutral Red Uptake Phototoxicity Test — Research Paper | ScholarLens