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2011•Chinese Journal of New Drugs and Clinical RemediesRequires access

Acute toxicity of liguzinediol

Wei Li

Open publisher page 4 citations

Abstract

AIM To investigate the acute toxicity of liguzinediol.METHODS Lethal dose 50(LD_(50))of liguzinediol was determinated by administration of tail vein in mice.The LD_(50)and 95%confidence interval were determined by data processing system.RESULTS LD_(50)of female and male mice were 1.592 1 g ? kg~(-1)and 1.692 2 g·kg~(-1),respectively.CONCLUSION Liguzindiol has low toxicity and wide safety range.

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What this paper is about

AIM To investigate the acute toxicity of liguzinediol.METHODS Lethal dose 50(LD_(50))of liguzinediol was determinated by administration of tail vein in mice.The LD_(50)and 95%confidence interval were determined by data processing system.RESULTS LD_(50)of female and male mice were 1.592 1 g ? kg~(-1)and 1.692 2 g·kg~(-1),respectively.CONCLUSION Liguzindiol has low toxicity and wide safety range.

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Available abstract

AIM To investigate the acute toxicity of liguzinediol.METHODS Lethal dose 50(LD_(50))of liguzinediol was determinated by administration of tail vein in mice.The LD_(50)and 95%confidence interval were determined by data processing system.RESULTS LD_(50)of female and male mice were 1.592 1 g ? kg~(-1)and 1.692 2 g·kg~(-1),respectively.CONCLUSION Liguzindiol has low toxicity and wide safety range.

Key concepts: Toxicity, Acute toxicity, Median lethal dose, Medicine, Confidence interval, Pharmacology, Toxicology, Internal medicine

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