2008•GuihaiaRequires access

Chemical components of diterpenoids from Isodon japonica var.galaucocalyx from Gansu Province, China

Han Wang

Abstract

Chemical constituents of diterpenoids from Isodon japonica var.galaucocalyx were studied. The compounds were isolated by column Chromatography and the structures of these compounds were elucidated by means of spectral analysis. The antitumor activity was determined in vitro by the SRB assay. Five compounds were isolated and identified as Rabdesinate(Ⅰ),Epinodosin(Ⅱ),Lasiokaourin(Ⅲ),Epinodosinol(Ⅳ) and Oridonin(Ⅴ),respectively. These compounds have significant cytotoxicity against Bel-7402 and HO-8910. Compounds Ⅲ,Ⅳ,Ⅴ of them were obtained form I.japonica var.galaucocalyx for the first time.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Japonica, Chemistry, Column chromatography, Cytotoxicity, Traditional medicine, Stereochemistry, Spectral analysis, Botany