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2015•Unpublished venueRequires access

The preparation of Thermosensitive in Situ Gel of Iodine

Liu Nin

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Abstract

objective:To Investigate the preparation, dissolution and release in vitro of thermosensitive in situ gel of iodine.Methods:Using orthogonal test method for screening the best prescription;Using the formula of gel accumulative dissolution percentage=(W1-Wt) /(W1-W0) to calculate the dissolution rate of Q by membrane-free; Calculating the accumulative release rate by the standard curve.As time increases, the dissolution rate and the release rate of the gel increased significantly.Conclusion:Thermosensitive in situ gel of iodine has good sustained re-lease effect.

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What this paper is about

objective:To Investigate the preparation, dissolution and release in vitro of thermosensitive in situ gel of iodine.Methods:Using orthogonal test method for screening the best prescription;Using the formula of gel accumulative dissolution percentage=(W1-Wt) /(W1-W0) to calculate the dissolution rate of Q by membrane-free; Calculating the accumulative release rate by the standard curve.As time increases, the dissolution rate and the release rate of the gel increased significantly.Conclusion:Thermosensitive in situ gel of iodine has good sustained re-lease effect.

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Available abstract

objective:To Investigate the preparation, dissolution and release in vitro of thermosensitive in situ gel of iodine.Methods:Using orthogonal test method for screening the best prescription;Using the formula of gel accumulative dissolution percentage=(W1-Wt) /(W1-W0) to calculate the dissolution rate of Q by membrane-free; Calculating the accumulative release rate by the standard curve.As time increases, the dissolution rate and the release rate of the gel increased significantly.Conclusion:Thermosensitive in situ gel of iodine has good sustained re-lease effect.

Key concepts: Dissolution, In situ, Iodine, Chemistry, Chromatography, Materials science, Organic chemistry

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