Clinical observation on the efficiency of dezocine with remifentanil and flurbiprofen for abdominal postoperative analgesia

OBJECTIVE To evaluate the efficiency and safety of dezocine with remifentanil and flurbiprofen for abdominal postoperative analgesia.METHODS 80 patients for elective abdominal operation,ASA Ⅰ-Ⅱ,were randomly divided into two groups,each group had 40 patients.The recipe in the independent intravenous analgesic pump was: control group,remifentanil 0.1 mg+ flurbiprofen 100 mg;observation group,dezocine 25 mg+ remifentanil 0.05 mg+ flurbiprofen 100 mg anesthesia was induced by midazolam,etomidate and rocuronium,maintained with propofol.10 min before the end of surgery,flurbiprofen 50 mg was given IV.Pain relief scores,sedation and side effects were recorded at 4,8,24,48 h after surgery.RESULTS Significantly higher pain relief scores(P0.05) were reported for the observation group than the control group at all observation times.Significantly better sedation scores were shown in observation group(P0.05).During the observation period,side effects happened in observation group were less than those in control group(P0.05).CONCLUSION Dezocine 25 mg + remifentanil 0.05 mg+flurbiprofen 100 mg group is better to relief the postoperative pain,and with less adverse effects.