Observation on Clinical Effects of Platelet Transfusion

Objective Through the determination of appropriate indicators before and after clinical platelet transfusion,observe its infusion effect,analyze the clinical indication before platelet transfusion to effect platelet increment.Methods 64 patients of 24h before and after infusion use cell counting instrument to calculate the corrected count increment platelet(CCI),observe the efficacy of platelet transfusion in 64 patients with 101 cases.Results According to the calculation of 24 h corrected count increment after infusion,the platelet transfusion refractoriness incidence of platelet transfusion is 36.63%,the detection rate of platelet-associated antibody is 37.84%.In regression analysis,the X1,X2,X3 become the main clinical indications to platelet transfusion.Conclusion The platelet radix before clinical platelet transfusion is larger variation,there exist abuse;the therapeutic effect of platelet transfusion is positively correlated to infusion frequency,with the increase of infusion,the probability of platelet antibody will increase;X1,X2,X3 are the main factors to impact the clinical infusion efficacy,the best approach to improve therapeutic effect is to develop an unified clinical platelet transfusion indication.