2000Chinese Journal of New Drugs and Clinical RemediesRequires access

Cost-effectiveness analysis of cefepime vs ceftazidime in treatment of pneumonia

Xiang Li

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Abstract

AIM: To compare the efficacy and cost of cefepime vs ceftazidime in treating moderate severe pneumonia. METHODS: Fifty six patients were randomly divided into 2 groups. Twenty eight patients (M 26, F 2; age 79 a± s 6 a) were treated with cefepime 1.0 g iv, gtt, bid, for 7-10 d. Another twenty eight patients (M 25,F 3;age 78 a±4 a) were treated with ceftazidime 1.0 g iv, gtt, tid, for 7-10 d. RESULTS: The clinical effective rates of cefepime and ceftazidime were similar, 96% vs 93% respectively ( P 0.05), but the cost for ceftazidime was higher than that for cefepime 6924 Yuan±702 Yuan vs 5504 Yuan±615 Yuan, ( P 0.05). CONCLUSION: The ceftazidime has similar effect to cefepime, but its cost is higher.

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AIM: To compare the efficacy and cost of cefepime vs ceftazidime in treating moderate severe pneumonia. METHODS: Fifty six patients were randomly divided into 2 groups. Twenty eight patients (M 26, F 2; age 79 a± s 6 a) were treated with cefepime 1.0 g iv, gtt, bid, for 7-10 d. Another twenty eight patients (M 25,F 3;age 78 a±4 a) were treated with ceftazidime 1.0 g iv, gtt, tid, for 7-10 d. RESULTS: The clinical effective rates of cefepime and ceftazidime were similar, 96% vs 93% respectively ( P 0.05), but the cost for ceftazidime was higher than that for cefepime 6924 Yuan±702 Yuan vs 5504 Yuan±615 Yuan, ( P 0.05). CONCLUSION: The ceftazidime has similar effect to cefepime, but its cost is higher.

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Available abstract

AIM: To compare the efficacy and cost of cefepime vs ceftazidime in treating moderate severe pneumonia. METHODS: Fifty six patients were randomly divided into 2 groups. Twenty eight patients (M 26, F 2; age 79 a± s 6 a) were treated with cefepime 1.0 g iv, gtt, bid, for 7-10 d. Another twenty eight patients (M 25,F 3;age 78 a±4 a) were treated with ceftazidime 1.0 g iv, gtt, tid, for 7-10 d. RESULTS: The clinical effective rates of cefepime and ceftazidime were similar, 96% vs 93% respectively ( P 0.05), but the cost for ceftazidime was higher than that for cefepime 6924 Yuan±702 Yuan vs 5504 Yuan±615 Yuan, ( P 0.05). CONCLUSION: The ceftazidime has similar effect to cefepime, but its cost is higher.

Key concepts: Cefepime, Ceftazidime, Medicine, Pneumonia, Internal medicine, Gastroenterology, Biology, Bacteria

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