2009•China Medical EngineeringRequires access

The effect of sildenafil to pulmonary hypertension with congenital heart disease in children

Long Xiang-pen

Abstract

Objective To study the effect and safety sildenafil to pulmonary hypertension with congenital heart disease in children.Methods22 children with congenital heart disease were included in the study from Jan 2006 to Dec 2007. The PASP, HR, CO, LVEF and LVFS were studied after sildenafil administration. And the adverse effects of all children within 24 hours after sildenafil administration. ResultsOral sildenafil can decrease the PASP of PH with CHD and no apparent adverse effects were observed in all children after sildenafil administration.Conclusions Sildenafil is effective and safety for the treatment of PH with CHD.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Sildenafil, Medicine, Pulmonary hypertension, Heart disease, Adverse effect, Cardiology, Internal medicine, Anesthesia