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2015•China Continuing Medical EducationRequires access

Expression of SOX9 and NM23 Gene in Prostate Cancer

Ren Caihon

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Abstract

Objective To investigate the expression of SOX9 and NM23 gene in prostate cancer.Methods 16 patients with prostate cancer and 24 patients with benign prostatic hyperplasia,take the pathological tissue,the expression of mRNA was measured by real-time fluorescence quantitative PCR.Results The expression of SOX9 and mRNA NM23 in prostate cancer group was significantly higher compared with that in patients with benign prostatic hyperplasia(P0.05).Conclusion The expression of SOX9 and mRNA NM23 can be measured,and it can provide reliable basis for clinical diagnosis of prostate cancer.

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What this paper is about

Objective To investigate the expression of SOX9 and NM23 gene in prostate cancer.Methods 16 patients with prostate cancer and 24 patients with benign prostatic hyperplasia,take the pathological tissue,the expression of mRNA was measured by real-time fluorescence quantitative PCR.Results The expression of SOX9 and mRNA NM23 in prostate cancer group was significantly higher compared with that in patients with benign prostatic hyperplasia(P0.05).Conclusion The expression of SOX9 and mRNA NM23 can be measured,and it can provide reliable basis for clinical diagnosis of prostate cancer.

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Available abstract

Objective To investigate the expression of SOX9 and NM23 gene in prostate cancer.Methods 16 patients with prostate cancer and 24 patients with benign prostatic hyperplasia,take the pathological tissue,the expression of mRNA was measured by real-time fluorescence quantitative PCR.Results The expression of SOX9 and mRNA NM23 in prostate cancer group was significantly higher compared with that in patients with benign prostatic hyperplasia(P0.05).Conclusion The expression of SOX9 and mRNA NM23 can be measured,and it can provide reliable basis for clinical diagnosis of prostate cancer.

Key concepts: Medicine, Prostate cancer, Hyperplasia, Pathological, PCA3, Prostate, SOX9, Real-time polymerase chain reaction

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