Effect research on enteral and parenteral nutrition support in treatment of severe acute pancreatitis

Objective To discuss the clinical treatment feasibility and effect of enteral and parenteral nutrition support in treatment of severe acute pancreatitis(SAP). Methods 65 patients with SAP were randomly divided into research group(33 cases) and control group(32 cases). The research group was given enteral nutrition support treatment, while the control group was given parenteral nutrition support treatment. The APACHE score, defecation time, abdominal pain disappear time, incidence of complications and fatality rate of two groups were compared. Results There were no significant difference in the APACHE score before treatment and treatment day between two groups (P 0.05). The APACHE score decreased gradually with the increasing of treatment days. The APACHE score in four days and seven days after treatment in research group were lower than that in control group(P 0.05), especially seven days after treatment(P 0.01). The defecation time and abdominal pain disappear time in research group were shorter than that in control group(P 0.01), while the incidence of complications and fatality rate in research group were lower than that in control group (P 0.05). There was no significant difference in the transfer operation rate between two groups (P 0.05). Conclusion The clinical effect of SAP treated with enteral nutrition support is superior to parenteral nutrition support, but enteral nutrition support treatment isn't very good for taking at the early stage, so enteral combined with parenteral nutrition support treatment should be taken for better clinical effect.