2009Suzhou Daxue xuebao. Yixue banRequires access

The Role of Enteral Nutrition Support in Treatment of Acute Severe Pancreatitis

Hua Chen

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Abstract

Objective To investigate the role of enteral nutrition support in treatment of acute severe pancreatitis. Methods The data on 30 patients with SAP were retrospectively analyzed. They were randomly assigned to receive either enteral nutrition (EN group,n=16)or total parenteral nutrition (TPN group, n =14). The changes of clinical indicators and clinical outcome were recorded. Results Two weeks after nutritional support, the APACHE II score and CTSI score were significantly lower in the EN group than in the TPN group(P0.01). The blood glucose,serum albumin , the blood calcium and serum creatinine in both groups were notably improved (P0.01),however,no significant difference was found between these two groups(P0.05). The average hospital stay was also notably shortened in the EN group. The incidence of shift to operation, complications and mortality were significantly lower in the EN group than in the TPN group (P 0.05). Conclusion Enteral nutrition is safe and effective in the treatment of SAP.

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Objective To investigate the role of enteral nutrition support in treatment of acute severe pancreatitis. Methods The data on 30 patients with SAP were retrospectively analyzed. They were randomly assigned to receive either enteral nutrition (EN group,n=16)or total parenteral nutrition (TPN group, n =14). The changes of clinical indicators and clinical outcome were recorded. Results Two weeks after nutritional support, the APACHE II score and CTSI score were significantly lower in the EN group than in the TPN group(P0.01). The blood glucose,serum albumin , the blood calcium and serum creatinine in both groups were notably improved (P0.01),however,no significant difference was found between these two groups(P0.05). The average hospital stay was also notably shortened in the EN group. The incidence of shift to operation, complications and mortality were significantly lower in the EN group than in the TPN group (P 0.05). Conclusion Enteral nutrition is safe and effective in the treatment of SAP.

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Available abstract

Objective To investigate the role of enteral nutrition support in treatment of acute severe pancreatitis. Methods The data on 30 patients with SAP were retrospectively analyzed. They were randomly assigned to receive either enteral nutrition (EN group,n=16)or total parenteral nutrition (TPN group, n =14). The changes of clinical indicators and clinical outcome were recorded. Results Two weeks after nutritional support, the APACHE II score and CTSI score were significantly lower in the EN group than in the TPN group(P0.01). The blood glucose,serum albumin , the blood calcium and serum creatinine in both groups were notably improved (P0.01),however,no significant difference was found between these two groups(P0.05). The average hospital stay was also notably shortened in the EN group. The incidence of shift to operation, complications and mortality were significantly lower in the EN group than in the TPN group (P 0.05). Conclusion Enteral nutrition is safe and effective in the treatment of SAP.

Key concepts: Parenteral nutrition, Medicine, Acute pancreatitis, Creatinine, Gastroenterology, Internal medicine, Incidence (geometry), Pancreatitis

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