Impacts of Huaiqihuang Granules on Humoral Immunity and Cellular Immunity in Children Nephrotic Syndrome

Objective To observe the changes in humoral immunity and cellular immunity in children nephrotic syndrome(NS) treated with Huaiqihuang Granules.Methods The NS inpatients were selected from June 2011 to June 2012.The humoral immunity,cellular immunity,serum albumin,24h urine protein and infection frequency were observed in Huaiqihuang Granules group.Results 1.In the 6th month,the significant effects were achieved on humoral immunity and cellular immunity in Huaiqihuang Granules group(P 0.05).In the 4th month,the effect was indicated on humoral immunity(P 0.05),rather than cellular immunity(P 0.05) in Huaiqihuang Granules group.2.The level of plasma albumin was increased after treatment in the two groups.In the 1st and 2nd months,the level of plasma albumin was increased apparently in Huaiqihuang Granules group(P 0.01).But the difference was not significant in the 4th and 6th months between the two groups(P 0.05).3.The level of 24h urine protein was reduced after treatment in the two groups as compared with that before treatment.The difference was significant in the 1st and 2nd months between the two groups(P 0.05).But the difference was not significant in the 4th and 6th months between the two groups(P 0.05).Conclusion Huaiqihuang Granules intensifies body resistance,reduces infection frequency and plays a certain effect of increasing serum albumin and reducing urine protein.