Clinical analysis of 159 patients with cervical intraepithelial neoplasia diagnosed and treated by cervical conization

Objective:To evaluate the application value of cervical conization in diagnosis and treatment of cervical intraepithelial neoplasia(CIN).Methods:Clinical data and follow-up results of 159 cases were analysed retrospectively.Results:138 cases and 21 cases were treated by LEEP conization and cold-knife conization,respectively,there was significant difference in surgery time and intraoperative blood loss(P0.01);5 cases(3.14%) had large blood loss in stadium decrustation,including 4 cases after LEEP conization and 1 case after cold-knife conization;after conization,the amount of pathologic degradation,unchanged and upgradation were 69 cases(43.40%),76 cases(47.80%) and 14 cases(8.80%,including 2 cases of invasive cervical carcinoma);there was significant difference in the proportion of smooth cervix between LEEP conization group(135 cases,97.82%) and cold-knife conization group(17 cases,80.95%) after 3 months(P0.05);cytologic follow-up was carried out on the third and sixth month after conization,3 cases relapsed,the cure rate was 98.11%,no infection,cervical adhesion and stenosis occurred.Conclusion:Masting the indications and techniques of cervical conization correctly may avoid missed diagnosis and increase success rate of CIN.