Cervical Conization for Cervical Intraepithelial Neoplasia

Objective To evaluate the efficacy of cervical conization in the treatment of different grade of cervical intraepithelial neoplasia(CIN). Methods All 142 cases CIN treated by cervical conization were retrospectively analyzed. Operation time,blood loss during the operation,changes of histopathologic results and high-risk HPV before and after the operation were studied. The diagnosis and treatment results by cervical conization were evaluated. Results The average operation time and blood loss by using Ioop electrosurgical excision procedure(LEEP) were less than those by cold knife conization significantly(P0.05). The concordance rate of histopathologic results under colposcope before operation and after cervical conization was 71.12%(101/142). Fifteen cases had increased CIN grade after cervical conization(10.56%). The HPV-DNA loading dose after operation was significantly declined(P 0.01). Conclusion The detection rate of invasive cervical cancer by cervical conization is higher than multiple punch biopsy under electronic colposcope.Cervical conization is an effective method for the diagnosis and treatment of CIN,and it can eliminate high-risk HPV and,at the same time,remove the cervical lesion.