A clinical study on the combination of tamsulosin and finasteride in treating patients with prostatic hyperplasia after TURP surgery

Objective To explore the effect of the combination of tamsulosin and finasteride or a drug alone on patients with benign prostatic hyperplasia after transurethral resection of the prostate(TURP).Methods One hundred twenty patients who underwent TURP surgery in our hospital from January 2010 to June 2011 were randomly divided into group A(tamsulosin alone),group B(finasteride alone),and group C(combination of tamsulosin and finasteride).Each group had 40 cases.The parameters such as international prostate symptom score(IPSS),maximum urinary flow rate(MFR) and prostate volume were determined in all patients before and 6 months after treatment.Results The parameters were statistically significant before and after treatment in all three groups(P 0.05).No significant difference in the parameters was found between group A and group B,but significant difference was discovered between group C and group A or group C and group(P0.05).Conclusions Tamsulosin or finasteride can improve the clinical symptoms of benign prostatic hyperplasia after TURP surgery.Combination of the two drugs has a better effect than a drug alone.