CT、MRI Findings of Congenital Eyeball Malformation

Objective To analyse CT and MRI findings of patients with congenital eyeball malformation and to explore the clinic values. Materials and Methods CT and /or MRI findings in 24 patients(31 eyes)were analyzed retrospectively. Axial CT scanning were performed in 9 cases, Axial and Coronal CT in 4 cases simultaneously, and MR was performed in 11 cases. Results Coloboma was depicted in 16 eyes, with typical protrusion of vitreous, resulting from focal defect of posterior globe at optic nerve head insertion. Among them retinal detachment was demonstrated in 2 eyes, orbital cyst in 9 eyes and hypoplastic of corpus callosum in 1 eye respectively. PHPV was visualized in 7 eyes with features including microphthalmus,retrolental tissue and persistent hyaloid artery. Coats' disease was revealed in 2 eyes with features of hyperdensity substance posterior to the vitreous on CT or hyperintense on T1WI and T2WI MR. Pure microphthalmus was delineated in 3 eyes. Anophthalmus was observed in 2 eyes. Conclusion CT and MR imaging provide valuable information to differentiate congenital eyeball malformation from other orbital pathologies, particularly from retinoblastoma.