Magnetic resonance imaging findings of congenital microphthalmos

Objective To evaluate MR imaging findings of congenital microphthalmos.Methods MR imaging findings of 15 cases(17 eyes) with microphthalmos confirmed by follow-up results were retrospectively analyzed.FSE T1 and T2 weighted imaging were performed in 15 patients,in which 3 cases were performed with postcontrast T1-weighted imaging.Results Among the 15 cases(17 eyes),unilateral microphthalmos was found in 13 cases,and bilateral microphthalmos was found in 2 cases.Colobomatous microphthalmia was found in 11 eyes,in which microphthalmos with coloboma of optic disc and a cyst with long T1 long T2 signal outstretching from the defect were found in 10 eyes,microphthalmos with a large orbital cyst was found in 1 eye.Complicated microphthalmia with PHPV was found in 5 eyes.Pure microphthalmia was found in 1 eye.Affected orbital cavity was diminished in 11 eyes,enlarged in 2 eyes,unchanged in 4 eyes.There was abnormality in visual pathway or intracalvarium in 4 cases.Conclusion MRI can display the microphthalmos and other dysplasia in orbit and central nervous system,contributing to diagnosis and therapy.