Risk factors of hematoma enlargement after hypertensive intracerebral hemorrhage

Objective:To explore the risk factors of hematoma enlargement after hypertensive intracerebral hemorrhage.Methods:122 patients with hypertensive intracerebral hemorrhage were analyzed,who came to our hospital from January 2009 to December 2010.Cranial CT scan within 6 hours and 48 hours was performed respectively after intracerebral hemorrhage.All patients were divided into hematoma enlargement group and non-hematoma enlargement group by head CT findings.Blood pressure within 24 hours after admission and mean arterial pressure,the first hematoma volume,hematoma shape,hematoma location,coagulation,and the use of osmotic diuretics were detected and analyzed.Results:Mean arterial pressure and the first hematoma volume(142.75 mmHg±19.69 mmHg,18.70 ml±6.25 ml) were significantly increased in hematoma enlargement group compared with non-hematoma enlargement group(121.08 mmHg±18.98 mmHg,13.10 ml±4.99 ml).The patients in hematoma enlargement group showed higher incidence than non-hematoma enlargement group in irregular hematoma shape,coagulation disorders and early use of osmotic diuretics.Hematoma location had no significant effect on hematoma enlargement.Conclusion:High mean arterial pressure,the first hematoma volume,irregular hematoma shape,coagulation dysfunction and early use of osmotic diuretics may be related to the hematoma enlargement after hypertensive intracerebral hemorrhage.