Effects of Heat Stress on the Building of Hippocampus Cells in Mice

The effects of heat stress on the morphology and structure of ganular and pyramidal cells in mice's hippocampus was explored by the technology of paraffin section and Nissl staining.The results showed that great changes of body size were observed in ganular and pyramidal cells four regions in hippocampal in the heat group.The body size of hippocampal CA3 pyramidal cell of the heat group was significantly smaller than that of the control group(P 0.01).Changes of the short axis was more significant than those of the long axis(p0.05) in ganular and pyramidal cells of four regions in hippocampal in heat group.Such phenomenon as the disordered arrangement, poor polarity, the reduction of the cell volume and area and the shrinkage of the cell membrane can be identified in ganular and pyramidal cells in heat stress mice under the light microscopy after Nissl staining.The results showed that heat stress can exert a great effect on the changes of morphology and structure of ganular and pyramidal cells in hippocampus, which is likely to be the pathology basis for cerebral injury after heat stress.