Analysis of prenatal sonography in screening Down syndrome and trisomy 18

Objective To assess the effectiveness of sonographic screening and discuss sonographic characteristics of Down syndrome and trisomy 18. Methods The subjects were recruited from pregnant women undergoing prenatal sonographic examinations and subsequently proven to be Down syndrome and trisomy 18 by genetic results. Results The results of ultrasound findings in 22 cases confirmed as Down syndrome and 8 cases confirmed as trisomy 18 were retrospectively reviewed. Conclusion Fetal sonography is a practical and effective prenatal screening method for detecting Down syndrome and trisomy 18.