Clinical Implications of Plasma Urotensin II and Serum C-reactive Protein Levels in Patients with Pregnancy-induced Hypertension Syndrome

Objective To explore the clinical implications of plasma urotensin Ⅱ (UⅡ) and serum C-reactive protein (CRP) levels in patients with pregnancy-induced hypertension syndrome (PIH). Methods The levels of plasma UⅡ and CRP in 30 PIH patients, 30 normal pregnant women and 30 non-pregnant healthy women were detected by enzyme-linked immunoassay (ELISA). Results The levels of plasma UⅡ and serum CRP in PIH patients were significantly higher than those in the other two groups (P0.01). There was significant correlation between UⅡ and CRP levels in PIH patients (r=0.893, P0.01).Conclusion Detection of plasma UⅡ and serum CRP in PIH patients avails for the exploration of the vascular endothelial cell damage and inflammation reaction degree, and prevention and early treatment of PIH.