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Analysis of the active compounds of Panax notoginseng and Salviae miltiorrhizae in Danxinshu capsules

Shengwang Liang

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Abstract

Objective To analyze the active compounds of Panax notoginseng and Salviae miltiorrhizae in Danxinshu capsules.Methods HPLC was used to analyze the contents of ginsenoside Rg_1 and Rb_1,notoginsenoside R_1 and tanshinoneⅡA in Danxinshu capsules. Results The linear ranges of ginsenoside Rg_1,ginsenoside Rb_1,notoginsenoside R_1 and tanshinoneⅡA were 0.924～9.24,0.736～7.36,0.21～2.10 and 0.04～0.40μg with average recoveries of 100.19% (RSD=1.67%),100.55% (RSD=1.29%), 100.21% (RSD=1.55%) and 100.79% (RSD=1.40%),respectively.Conclusion The method is simple,reliable and stable, which could be used for the quality control of Danxinshu capsules.

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What this paper is about

Objective To analyze the active compounds of Panax notoginseng and Salviae miltiorrhizae in Danxinshu capsules.Methods HPLC was used to analyze the contents of ginsenoside Rg_1 and Rb_1,notoginsenoside R_1 and tanshinoneⅡA in Danxinshu capsules. Results The linear ranges of ginsenoside Rg_1,ginsenoside Rb_1,notoginsenoside R_1 and tanshinoneⅡA were 0.924～9.24,0.736～7.36,0.21～2.10 and 0.04～0.40μg with average recoveries of 100.19% (RSD=1.67%),100.55% (RSD=1.29%), 100.21% (RSD=1.55%) and 100.79% (RSD=1.40%),respectively.Conclusion The method is simple,reliable and stable, which could be used for the quality control of Danxinshu capsules.

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Available abstract

Objective To analyze the active compounds of Panax notoginseng and Salviae miltiorrhizae in Danxinshu capsules.Methods HPLC was used to analyze the contents of ginsenoside Rg_1 and Rb_1,notoginsenoside R_1 and tanshinoneⅡA in Danxinshu capsules. Results The linear ranges of ginsenoside Rg_1,ginsenoside Rb_1,notoginsenoside R_1 and tanshinoneⅡA were 0.924～9.24,0.736～7.36,0.21～2.10 and 0.04～0.40μg with average recoveries of 100.19% (RSD=1.67%),100.55% (RSD=1.29%), 100.21% (RSD=1.55%) and 100.79% (RSD=1.40%),respectively.Conclusion The method is simple,reliable and stable, which could be used for the quality control of Danxinshu capsules.

Key concepts: Panax notoginseng, Chemistry, Ginsenoside Rg1, Ginsenoside, Chromatography, High-performance liquid chromatography, Traditional medicine, Ginseng

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