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Association of nonalcoholic fatty liver disease with obesity and insulin resistance

Qing Liu

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Abstract

Objective To study the relationship between nonalcoholic fatty liver disease (NAFLD),obesity and insulin resistance.Method High,weight,waist circumference(WI),hip circumference(HI),serum lipid,fasting and2-hour postprandial blood glucose and insulin were detected in59patients with typeⅡdiabetes accompanying fatty liver(DF),43patients with typeⅡdiabetes without fatty liver(NDF).Body mass index(BMI),waist-hip ratio(WHR)and insulin resistance index(HOMA-IR)were calculated.Data were statistically analyzed.Results The results showed that BMI,WI,WHR,TC,TG,fasting insulin(FINS)and HOMA-IR were signifi-cantly elevated in the subjects of DF,compared with those of NDF (P0.05).Conclusion NAFLD were intimately associated with obesity and insulin resistance.

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What this paper is about

Objective To study the relationship between nonalcoholic fatty liver disease (NAFLD),obesity and insulin resistance.Method High,weight,waist circumference(WI),hip circumference(HI),serum lipid,fasting and2-hour postprandial blood glucose and insulin were detected in59patients with typeⅡdiabetes accompanying fatty liver(DF),43patients with typeⅡdiabetes without fatty liver(NDF).Body mass index(BMI),waist-hip ratio(WHR)and insulin resistance index(HOMA-IR)were calculated.Data were statistically analyzed.Results The results showed that BMI,WI,WHR,TC,TG,fasting insulin(FINS)and HOMA-IR were signifi-cantly elevated in the subjects of DF,compared with those of NDF (P0.05).Conclusion NAFLD were intimately associated with obesity and insulin resistance.

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Available abstract

Objective To study the relationship between nonalcoholic fatty liver disease (NAFLD),obesity and insulin resistance.Method High,weight,waist circumference(WI),hip circumference(HI),serum lipid,fasting and2-hour postprandial blood glucose and insulin were detected in59patients with typeⅡdiabetes accompanying fatty liver(DF),43patients with typeⅡdiabetes without fatty liver(NDF).Body mass index(BMI),waist-hip ratio(WHR)and insulin resistance index(HOMA-IR)were calculated.Data were statistically analyzed.Results The results showed that BMI,WI,WHR,TC,TG,fasting insulin(FINS)and HOMA-IR were signifi-cantly elevated in the subjects of DF,compared with those of NDF (P0.05).Conclusion NAFLD were intimately associated with obesity and insulin resistance.

Key concepts: Medicine, Insulin resistance, Internal medicine, Nonalcoholic fatty liver disease, Waist, Type 2 diabetes, Postprandial, Endocrinology

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