ScholarLens Back to search
2006•Chinese Journal of Laboratory DiagnosisRequires access

Inhibiting effects of genistein in human hepatocaycinoma cell line SMMC-7721

Tian Xiao

Open publisher page 0 citations

Abstract

Objective To investigate the effect of genistein on human hepatocarcinoma cell line SMMC-7721.Methods The effect of genistein on the growth of SMMC-7721 cells was evaluated by MTT assay in vitro,cell cycle analysis and characteristic ultrastructural alterations.Results Genistein was effective in inhibiting the proliferation of SMMC-7721 cells.Cell cycle analysis indicated that the number of cells was increased in G2/M phase.The inhibitory effect of genistein was confimed by characteritic ultrastructural alterations.Conclusion Genistein inhibits the proliferation of hepatocarcinoma cell line SMMC-7721 in vitro mainly by altering the cell cycle and ultrastructure.

About this research paper

What this paper is about

Objective To investigate the effect of genistein on human hepatocarcinoma cell line SMMC-7721.Methods The effect of genistein on the growth of SMMC-7721 cells was evaluated by MTT assay in vitro,cell cycle analysis and characteristic ultrastructural alterations.Results Genistein was effective in inhibiting the proliferation of SMMC-7721 cells.Cell cycle analysis indicated that the number of cells was increased in G2/M phase.The inhibitory effect of genistein was confimed by characteritic ultrastructural alterations.Conclusion Genistein inhibits the proliferation of hepatocarcinoma cell line SMMC-7721 in vitro mainly by altering the cell cycle and ultrastructure.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the effect of genistein on human hepatocarcinoma cell line SMMC-7721.Methods The effect of genistein on the growth of SMMC-7721 cells was evaluated by MTT assay in vitro,cell cycle analysis and characteristic ultrastructural alterations.Results Genistein was effective in inhibiting the proliferation of SMMC-7721 cells.Cell cycle analysis indicated that the number of cells was increased in G2/M phase.The inhibitory effect of genistein was confimed by characteritic ultrastructural alterations.Conclusion Genistein inhibits the proliferation of hepatocarcinoma cell line SMMC-7721 in vitro mainly by altering the cell cycle and ultrastructure.

Key concepts: Genistein, Cell cycle, Cell culture, In vitro, Cell growth, Ultrastructure, Cell biology, Cell

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Inhibiting effects of genistein in human hepatocaycinoma cell line SMMC-7721 — Research Paper | ScholarLens