Empirical Studies on Quercetin for Inhibition of proliferation of SMMC-7721 cells of Hepatocarcinoma

Objective To investigate inhibition of quercetin on cell proliferation of SMMC-7721 cells of Hepatocarcinema.Methods Colorimetric MTT-assay was used to measure the Inhibition ratio of Quercetin on SMMC-7721 cells.The proliferation cycle of SMMC-7721 cells was determined using flow cytometry.Results Quercatin 10-320 μmol/L inhibited the proliferation,of SMMC-7721 cells with different rations and showed the time-and dose-dependent relationships.The augment of G1 ration in the proliferation cycle of SMMC-7721 cells presents a dose dependent manner.Conclusion Quercatin can inhibit the proliferation of SMMC-7721 cells and might induce the apoptosis by restrained cell cycle at G1.