Photodynamic Therapy and Sonodynamic Therapy

Objective:This paper summarized the research status and progress of photodynamic therapy(PDT) and sonodynamic therapy(SDT) ,and we hope this can be a useful reference for clinics or research. Methods:In this review we expound their molecular mechanisms in detail and classify the photosensitizer and sonosensitizer,indicate their applications for the cancer treatment and summarize their new treating modes. PDT and SDT have huge potential for cancer treatment. Results:PDT and SDT have achieved a certain results,whereas there are still many problems,such as tissue oxygen content,new photosensitizer and sonosensitizer,drug dosage and mechanisms of SDT. Conclusions:PDT and SDT,which are new methods for treating cancer,have shown a good application prospect. But PDT has not been universal in clinics and SDT is still in the experiment stage.