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2007•Journal of Clinical HematologyRequires access

Curative effect of intravenous injection gamma globulin threapy on idiopathic thrombocytopenic purpura

Dong-hua Mo

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Abstract

Objective:To investigate the curative effect of intravenous injection gamma globulin(IVIG) threapy on idiopathic thrombocytopenic purpura (ITP).Method:Dosage of IVIG was 0.4 g·kg-1·d-1on d1~5. Result:Among 25 patients, 11 patients (44%) with ITP achieved remarkably excellent effects, 5 patients (20%) arrived at elementary curement, 6 patients (24%) acquired good effects, 4 patients (16%) imporved and 4 patients (16%) were without response. Total effective rate was 84%.Conclusion:To severe or refractory ITP, IVIG was a safe, effective treatment without obvius side effect.Currative effect was much better in initial patients or those younger that 14 years old. IVIG could be used repeatedly. Glucocorticoid could be effective in those relapsing patients.

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What this paper is about

Objective:To investigate the curative effect of intravenous injection gamma globulin(IVIG) threapy on idiopathic thrombocytopenic purpura (ITP).Method:Dosage of IVIG was 0.4 g·kg-1·d-1on d1~5. Result:Among 25 patients, 11 patients (44%) with ITP achieved remarkably excellent effects, 5 patients (20%) arrived at elementary curement, 6 patients (24%) acquired good effects, 4 patients (16%) imporved and 4 patients (16%) were without response. Total effective rate was 84%.Conclusion:To severe or refractory ITP, IVIG was a safe, effective treatment without obvius side effect.Currative effect was much better in initial patients or those younger that 14 years old. IVIG could be used repeatedly. Glucocorticoid could be effective in those relapsing patients.

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Available abstract

Objective:To investigate the curative effect of intravenous injection gamma globulin(IVIG) threapy on idiopathic thrombocytopenic purpura (ITP).Method:Dosage of IVIG was 0.4 g·kg-1·d-1on d1~5. Result:Among 25 patients, 11 patients (44%) with ITP achieved remarkably excellent effects, 5 patients (20%) arrived at elementary curement, 6 patients (24%) acquired good effects, 4 patients (16%) imporved and 4 patients (16%) were without response. Total effective rate was 84%.Conclusion:To severe or refractory ITP, IVIG was a safe, effective treatment without obvius side effect.Currative effect was much better in initial patients or those younger that 14 years old. IVIG could be used repeatedly. Glucocorticoid could be effective in those relapsing patients.

Key concepts: Medicine, Thrombocytopenic purpura, Refractory (planetary science), Gamma globulin, Purpura (gastropod), Gastroenterology, Internal medicine, Surgery

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