Analysis of blood pressure in NIDDM

Objective To investigate further the relationship between diabetes mellitus Ⅱ (NIDDM) and blood pressure.Methods 24 hour ambulatory blood pressure was measured by ambulatory blood pressure monitor in 43 patients with diabetes mellitus and 46 normal controls in this hospital. Their 24 hour mean systolic pressure (24 h MSP),the 24 hour systolic pressure load (24 h SPL),the 24 hour mean diastolic pressure (24 h MDP),the 24 hour diastolic pressure load(24 h DPL),the daytime mean systolic pressure(dMSP),the daytime systolic pressure load(dSPL),the daytime mean diastolic pressure(dMDP),the daytime diastolic pressure load(dDPL),the nighttime mean systolic pressure (nMSP),the nighttime systolic pressure load(nSPL),the nighttime mean diastolic pressure(nMDP),nighttime diastolic pressure load (nDPL) and the circadian rhythm and fluctuation of blood pressure were statistically analysed.Results The 24 h MSP,dMSP,nMSP,24 h SPL,dSPL and nSPL in NIDDM group were significantly higher than those in controls(P0.01) and the detectable rates of non dipper and fluctuating blood pressure in NIDDM group were also significantly higher than those in the controls (P 0.01), while the 24 h MDP,dMDP,nMDP,24 h DPL,dDPL,nDPL presented no great difference between the two groups (P0.05).Conclusions The patients with NIDDM already have increased systolic blood pressure before the clinical hypertension,at the same time they also have allorhythmia of circadian blood pressure and fluctuation of blood pressure.In order to control the chronic complications of diabetes mellitus,the increased blood pressure must be controlled first and the abnormal rhythm of blood pressure must be corrected.In clinical practice,in order to discover this abnormality of blood pressure earlier and to treatment it earlier,it is better to use the ambulatory blood pressure monitor.