Synthesis of Ethyl Salicylate Catalyzed by Sodium Bisulfate under Certain Pressure

Ethyl salicylate was synthesized with sodium bisulfate as catalyst in autoclave.Different factors such as mole ratio of reactants,temperature and reaction time were studied by mono-factor test.The optimum reaction conditions were attained as follows: the amount of catalyst was 4% of total mass of reactants,mole ratio of ethanol to salicylic acid was 5∶1,reaction time was 4h,reaction temperature was 140℃ and pressure was 171kPa.The yield of ethyl salicylate reached 85%.Qualitative analysis of product was carried by IR and purity was above 99% analyzed by GC.