Research on the Bioactivity and Compressive Strength of Glass Based Bone Cement

Glass based bone cement(GBC) was synthesized by mixing CaO-SiO_2-P_2O_5 based glass powder with ammonium phosphate liquid. Phase compositions, chemical compositions and microstructure of the final products of GBC were measured and observed using X-ray diffraction(XRD),Fourier transform infrared spectroscope(FTIR) and scanning electronic microscope(SEM) respectively. The experiment shows that with a longer immersion time in simulated body fluid(SBF) the glass phase in GBC gradually changes to nano-size bone-like hydroxyapatite(HAP)crystallite with the end plane granularity 30～50 nm. Mechanical testing results show that the compressive strength of GBC increases with the proceeding of immersion in SBF(reaching 80 MPa after 30 d). It is clear that GBC is a desirable biomedical material for the repairing of bone defects with an excellent bioactivity and high (mechanical) strength.