Application of propofor combined with midazolam or fentanyl to endoscopy

Objective To compare the effiect of three kinds of methods,make sedation anesthesia and safty have the ahemative for easy endoscopy.Methods 90 patients were randomized into three groups,Group A used(propofor,midazolam and fentanyl group,n=30),Group B used(propofor,fentanyl group,n=30),Group C used(propofor group,n=30).Group A used midazolam 1mg iv combined with propoful 1.5mg/kg in 3mg/s speed and fentanyl 10μg/kg.Group B used fentanyl 10μg/kg combined with propofor 2mg/kg in 3mg/s.Group C used propofor 2mg/kg iv in 3mg/s.Heart rate,blood pressure and SpO2 were measured before the procedure and monitored continuously during and after the procedure.Results Group A presented on obvious sedation and anesthesia compared with Group B and C,P0.05.Conclusion Propofor combined with midazolam and fentanyl presents optimal effective in sedation and anesthesia for endoscopy.