Diagnostic Value of MRI Scanning,Dynamic Contrast-Enhanced MRI and Diffusion-Weighted MRI in Breast Diseases

Objective:To approach the value of MRI scanning,dynamic contrast-enhanced MRI(DCE-MRI)and diffusion-weighted MR imaging(DWI)in the diagnosis of breast diseases.Methods:Forty-seven breast lesions from forty-five patients,including thirty-one malignant lesions and sixteen benign lesions,were examined.The validities of dynamic contrast-enhanced imaging,ADC, and combination of the two methods were evaluated according to the histopathology result.Results:The sensitivity,specificity,and accuracy of MRI scanning and dynamic contrast-enhanced imaging respectively were 74.2%,87.1%,50% and 62.5%,66%,78.7%respectively.The threshold of ADC for diagnosis was 1.2×10-3 mm2/s by ROC analysis.The sensitivity,specificity,and accuracy of ADC were 93.6%,75%,and 87.2% respectively.The sensitivity,specificity and accuracy of combination of dynamic contrast-enhanced MRI and DWI-ADC were 83.9%,87.5% and 85.1% respectively.Conclusion:① The specificity of MRI scanning and dynamic contrast-enhanced MRI imaging is low,but the combination of dynamic contrast-enhanced MRI and DWI can increase the specificity.② The sensitivity of DWI is high,and it is helpful to screen the malignant breast lesions from the benign.Most ADC values of malignant brest lesions are no more than 1.2×10-3 mm2/s.