Preparation and Application of Silk Fibrion Scaffolds for Tissue Engineering

As a natural fibrous protein,silk fibroin has remarkable mechanical properties,biocompatibility and biodegradability,which makes it widely used in biomedical area.Porous scaffolds provide a favorable microenvironment for cell adhesion and proliferation and play a key role in the process of remodeling and repairing tissue.In this paper,a variety of preparation methods of silk fibroin scaffolds including electrospinning,freeze-drying,leaching and foaming.The surface modification of the silk fibroin scaffolds is described and the applications of silk fibroin scaffolds in tissue engineering are summarized.