Clinical meaning on pre and postoperative splanchnic hemodynamics in cirrhotic patients with portal hypertension
Gao De
Abstract
Gao De
Abstract
In this study, splanchnic hemodynamics were observed and analysed by duplex Doppler sonography in patients with liver cirrhosis before and after operation for portal hypertension. The results showed that portal and splenic vein diameter and blood flow volume were dialted and increased in cirrhotic patients with portal hypertension as compared with healthy subjects (P0. 0 1 ), fourthermore, increase of portal.vein blood flow was ppositively correlated with that of splenic vein. After nonshunting operation, portal vein diameter and blood flow volume were markedly reduced, as compared with controls, the difference was statistically significant (P 0. 01 ). Degree of the reduction of portal vein diameter was more significant in postoperation of nonshunting combined with splenorenal shunting than in postoperation of nonshuntiing, but decrease of portal blood flow was not significantly different between them. The results above indicated that nonshunt, and nonshunt combined with shunt,are all suitable for portal hypertention in cirrhosis.
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In this study, splanchnic hemodynamics were observed and analysed by duplex Doppler sonography in patients with liver cirrhosis before and after operation for portal hypertension. The results showed that portal and splenic vein diameter and blood flow volume were dialted and increased in cirrhotic patients with portal hypertension as compared with healthy subjects (P0. 0 1 ), fourthermore, increase of portal.vein blood flow was ppositively correlated with that of splenic vein. After nonshunting operation, portal vein diameter and blood flow volume were markedly reduced, as compared with controls, the difference was statistically significant (P 0. 01 ). Degree of the reduction of portal vein diameter was more significant in postoperation of nonshunting combined with splenorenal shunting than in postoperation of nonshuntiing, but decrease of portal blood flow was not significantly different between them. The results above indicated that nonshunt, and nonshunt combined with shunt,are all suitable for portal hypertention in cirrhosis.
Key concepts: Medicine, Portal hypertension, Splanchnic, Cirrhosis, Splenic vein, Hemodynamics, Splanchnic Circulation, Portal venous pressure