2013•China Medicine and PharmacyRequires access
Effectiveness and safety of simvastatin in the treatment of coronary heart disease in patients with dyslipidemia
Yu Pen
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Abstract
Objective To evaluate the effectiveness and safety of different dose of simvastatin in the treatment of coronary heart disease in patients with dyslipidemia.Methods Totol 86 patients with definite diagnosis of coronary heart disease were divided into two groups,43 patients in each group.The low dose group were treated with 20 mg simvastatin and high dose group with 40 mg simvastatin once each night.Analyzed the changes of lipids and the untoward reactions in two groups.Results The blood lipids were decreased significantly after 12 weeks treatment(P 0.05),and the lipid improvement in hign dose group was better than in low dose group(P 0.01).Conclusion Simvastatin could significantly improve the blood lipids and is relatively reliable in treatment of coronary heart disease.