An Experimental Study of the Side-to-side Neurorrhaphy to Repair Incomplete Injury of Peripheral Nerve
Xiu Xian
Abstract
Xiu Xian
Abstract
Objective: To describe a new method of side to side neurorrhaphy for the repair of peripheral nerve incomplete injury and study the effect after this procedure.Methods:12 SD rats were used;bilateral lower extremities of the animals as the operated specimens were randomly divided into experimental and control sides.The peroneal nerve of two side were clipped with identical strength,in experimental side,the distal segment was kept close to neighboring tibial nerve,and then the epineurium and perineurium of two neighboring segment were incised,at last,two nerve were anastomosed by side to side neurorrhaphy.The nerve regeneration was analyzed with electromyographic and histological examination after 3 months.Results:A large number of nerve fibers were found in the distal peroneal nerve of experimental side,the quality of the regenerated fibers exhibited significant difference from control side( P 0.01).Conclusion:The side to side neurorrhaphy was a new valuable method to repair incomplete injury of peripheral nerve.
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Objective: To describe a new method of side to side neurorrhaphy for the repair of peripheral nerve incomplete injury and study the effect after this procedure.Methods:12 SD rats were used;bilateral lower extremities of the animals as the operated specimens were randomly divided into experimental and control sides.The peroneal nerve of two side were clipped with identical strength,in experimental side,the distal segment was kept close to neighboring tibial nerve,and then the epineurium and perineurium of two neighboring segment were incised,at last,two nerve were anastomosed by side to side neurorrhaphy.The nerve regeneration was analyzed with electromyographic and histological examination after 3 months.Results:A large number of nerve fibers were found in the distal peroneal nerve of experimental side,the quality of the regenerated fibers exhibited significant difference from control side( P 0.01).Conclusion:The side to side neurorrhaphy was a new valuable method to repair incomplete injury of peripheral nerve.
Key concepts: Medicine, Epineurium, Perineurium, Surgery, Peripheral nerve, Epineurial repair, Peripheral nerve injury, Nerve repair