2015•China Medicine and PharmacyRequires access

Antihypertensive effect analysis of travoprost combined carteolol in the treatment of high intraocular pressure of primary angle closure glaucoma postoperative

Zhang Guinin

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Abstract

Objective To investigate antihypertensive effect analysis of travoprost combined carteolol in the treatment of high intraocular pressure of primary angle closure glaucoma patients after operation. Methods 64 patients(64 eyes)with PACG from April 2012 to April 2013 to accept the treatment in our hospital as the research object.According to the figures were randomly divided into a travoprost group and a carteolol group,the travoprost group was used 0.004% travoprost for treatment,the carteolol group was used 2% carteolol for treatment,intraocular pressure changes before and after treatment,percentage between the two groups before and after treatment and after treatment of intraocular pressure difference of intraocular pressure drop,the percentage of two groups of varying degrees of anterior chamber angle open patients before and after intraocular pressure difference after treatment and intraocular pressure drop were compared. Results Intraocular pressure after the treatment in the two groups was significantly lower than the values of each group before treatment, the difference was statistically significant(P 0.05).But the two groups before and after treatment between the groups compared with intraocular pressure value,the differences were not statistically significant(P 0.05).The percentage of travoprost group before and after treatment, intraocular pressure difference and intraocular pressure decreased after treatment were significantly higher than that in the control group,the difference was statistically significant(P 0.05).The percentage difference between the two groups with different levels of anterior chamber angle open patients before and after intraocular pressure difference and intraocular pressure decreased after treatment had no statistical significance(P 0.05).According to correlation analysis showed that Spearman method,the percentage of anterior chamber intraocular pressure difference before and after treatment and after treatment and the degree of opening of the intraocular pressure decreased angle had no obvious correlation. Conclusion Travoprost and carteolol can be used to reduce the high intraocular pressure in patients with PACG after operation, but the travoprost effect is better,and it is worthy of clinical application.

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What this paper is about

Objective To investigate antihypertensive effect analysis of travoprost combined carteolol in the treatment of high intraocular pressure of primary angle closure glaucoma patients after operation. Methods 64 patients(64 eyes)with PACG from April 2012 to April 2013 to accept the treatment in our hospital as the research object.According to the figures were randomly divided into a travoprost group and a carteolol group,the travoprost group was used 0.004% travoprost for treatment,the carteolol group was used 2% carteolol for treatment,intraocular pressure changes before and after treatment,percentage between the two groups before and after treatment and after treatment of intraocular pressure difference of intraocular pressure drop,the percentage of two groups of varying degrees of anterior chamber angle open patients before and after intraocular pressure difference after treatment and intraocular pressure drop were compared. Results Intraocular pressure after the treatment in the two groups was significantly lower than the values of each group before treatment, the difference was statistically significant(P 0.05).But the two groups before and after treatment between the groups compared with intraocular pressure value,the differences were not statistically significant(P 0.05).The percentage of travoprost group before and after treatment, intraocular pressure difference and intraocular pressure decreased after treatment were significantly higher than that in the control group,the difference was statistically significant(P 0.05).The percentage difference between the two groups with different levels of anterior chamber angle open patients before and after intraocular pressure difference and intraocular pressure decreased after treatment had no statistical significance(P 0.05).According to correlation analysis showed that Spearman method,the percentage of anterior chamber intraocular pressure difference before and after treatment and after treatment and the degree of opening of the intraocular pressure decreased angle had no obvious correlation. Conclusion Travoprost and carteolol can be used to reduce the high intraocular pressure in patients with PACG after operation, but the travoprost effect is better,and it is worthy of clinical application.

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Available abstract

Objective To investigate antihypertensive effect analysis of travoprost combined carteolol in the treatment of high intraocular pressure of primary angle closure glaucoma patients after operation. Methods 64 patients(64 eyes)with PACG from April 2012 to April 2013 to accept the treatment in our hospital as the research object.According to the figures were randomly divided into a travoprost group and a carteolol group,the travoprost group was used 0.004% travoprost for treatment,the carteolol group was used 2% carteolol for treatment,intraocular pressure changes before and after treatment,percentage between the two groups before and after treatment and after treatment of intraocular pressure difference of intraocular pressure drop,the percentage of two groups of varying degrees of anterior chamber angle open patients before and after intraocular pressure difference after treatment and intraocular pressure drop were compared. Results Intraocular pressure after the treatment in the two groups was significantly lower than the values of each group before treatment, the difference was statistically significant(P 0.05).But the two groups before and after treatment between the groups compared with intraocular pressure value,the differences were not statistically significant(P 0.05).The percentage of travoprost group before and after treatment, intraocular pressure difference and intraocular pressure decreased after treatment were significantly higher than that in the control group,the difference was statistically significant(P 0.05).The percentage difference between the two groups with different levels of anterior chamber angle open patients before and after intraocular pressure difference and intraocular pressure decreased after treatment had no statistical significance(P 0.05).According to correlation analysis showed that Spearman method,the percentage of anterior chamber intraocular pressure difference before and after treatment and after treatment and the degree of opening of the intraocular pressure decreased angle had no obvious correlation. Conclusion Travoprost and carteolol can be used to reduce the high intraocular pressure in patients with PACG after operation, but the travoprost effect is better,and it is worthy of clinical application.

Key concepts: Travoprost, Medicine, Intraocular pressure, Glaucoma, Ophthalmology, Ocular hypertension, Significant difference, Open angle glaucoma

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Antihypertensive effect analysis of travoprost combined carteolol in the treatment of high intraocular pressure of primary angle closure glaucoma postoperative — Research Paper | ScholarLens