Effects of treating uricacidemia by losartan in patients with hypertension associated hyperuricemia

Objective: To study the effects of by losartan in treating patients with hypertension associated with hyperuricemia.Methods: 96 patients with hypertension and were divided into two groups by random (group 1∶50cases, group2∶46cases). Group 1 included patients only taking.Group 2 included patients taking losartan combined other antihypertensive drugs including hydrochlorothiazide. 40cases patients taking captopril was control group. Observed the change of uricacidemia, uricacid in urine and urinary protein of two groups after treatment for 3 days, 1 week, 2 weeks and 4 weeks.Results: Uricacidemia had apparently reduced after losartan treatment for 3 days and the outage of 24 h uricacid had apparently increased with the outage of 24 h urnary protein decreasing.Conclusion: Losartan can be used for underpressure and treating uricacidemia and protection of kidneys.