Clinical Effect Observation of Escitalopram in the Treatment of Somatoform Disorders

Objective To explore the efficacy and safety of escitalopram in the treatment of somatoform disorders.Methods 44 patients with somatoform disorders were received escitalopram with an initial dosage of 10mg/d for 6 weeks.The Symptom Checklist 90(SCL-90) and Hamilton Depression Scale(HAMD)were conducted,the efficacy were assessed with the reduction rate of HAMD.Results After 2 weeks treatment efficiency was 31.8%,the 4 weekend efficiency is 63.6%,the 6 weekend efficiency is 81.8%.After 2 weeks treatment,comparison,somatization,depression,anxiety factor scores and factor before treatment,the difference had statistical significance(t=2.18,3.21,4.15,P0.05).In 4 weeks,6 weeks treatment,the factor scores compared with before treatment,the difference was statistically significant(P 0.05).Conclusion Escitalopram may rapidly relieve somatic discomfort and depression and anxiety,and with less adverse reactions.