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2011•Zhongguo linchuang yixueRequires access

Relationship between Insulin-Like Growth Factor 2(IGF-2) and Bone Mineral Density in Patients with Type2 Diabetes

Yingli Lu

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Abstract

Objective:To study the relationship between the serum level os insulin-like growth factor 2(IGF-2) and bone mineral density(BMD) in patients with type2 diabetes(DM).Methods:Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results:As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions:IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.

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What this paper is about

Objective:To study the relationship between the serum level os insulin-like growth factor 2(IGF-2) and bone mineral density(BMD) in patients with type2 diabetes(DM).Methods:Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results:As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions:IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.

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Available abstract

Objective:To study the relationship between the serum level os insulin-like growth factor 2(IGF-2) and bone mineral density(BMD) in patients with type2 diabetes(DM).Methods:Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results:As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions:IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.

Key concepts: Medicine, Internal medicine, Bone mineral, Endocrinology, Insulin-like growth factor, Osteoporosis, Diabetes mellitus, Insulin

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Relationship between Insulin-Like Growth Factor 2(IGF-2) and Bone Mineral Density in Patients with Type2 Diabetes — Research Paper | ScholarLens