The Effects of Various Concentrations of Hypertonic Saline on Brain Edema after Severe Traumatic Brain Injury

Objective: To explore the various concentrations of hypertonic saline on brain edema in patients with severe head trauma,increased intracranial pressure,cerebral perfusion pressure.Method: 160 patients,according to the different concentrations of hypertonic saline,were divided into 4 groups,each with 40 cases,continuous monitoring of patients with mean arterial pressure,intracranial pressure,comparing each group to reduce intracranial pressure enhance the effect of cerebral perfusion pressure.Result: 7.5% HS group rate of intracranial pressure was lower than the other three groups(P0.05),7.5% HS group rate of the average arterial pressure was significantly higher than the other three groups(P0.05),7.5% HS group rate of intracranial pressure was significantly lower than the other three groups(P0.05),7.5% HS group rate of cerebral perfusion pressure was significantly higher than the other three groups(P0.05).Conclusion: Four different concentrations of hypertonic saline can reduce brain edema after traumatic brain injury patients with intracranial pressure,increase cerebral perfusion pressure,but 7.5% HS is the best of all.