Cytokines and Liver Fibrosis

To comprehend the role of cytokines in occurrence and development of hepatic fibrosis. To summarize the action of many kinds of cytokines in occurrence and development of hepatic fibrosis by reviewing literatures. The cytokines which can influence occurrence and development of hepatic fibrosis may divide into two groups: to promote or to anti-hepatic fibrosis. These cytokines structure complex regulative nets, transmit signal by much signal transduction passway, and control the occurrence and development of hepatic fibrosis. Cytokines produce a marked effect in occurrence and development of hepatic fibrosis.