Effects of three kinds of crown materials on aspartate aminotransferase and alkaline phosphatase levels in gingival crevicular fluid

Objective:To further investigate the effects of three kinds of material on the level of aspartate aminotransferase(AST)and alkaline phosphatase(ALP)in gingival crevicular fluid(GCF).Methods:The anterior teeth and the premolar teeth of 30 patients were divided into three groups randomly for Co-Cr alloy PFM,Ti PFM and all ceramic crown.Before tooth preparation,1,3 and 6 months after cementation,GCF was collected at the same sites.The levels of AST and ALP were detected by automated chemical analyzer,and analyzed the variation between the pre-restoration and post-restoration.Results:Before tooth preparation and 1 month after cementation,all indexes showed no difference among three groups.The level of GCF,AST and ALP of Co-Cr alloy group showed conspicuous difference with Ti PFM and all ceramic crowns after 3 months and 6 months.However,the levels of GCF,AST and ALP of Ti PFM group showed no difference with all ceramic crowns.Conclusion:Co-Cr based PFM crowns which clinically accepted have lead to changes of the levels of GCF,AST and ALP.Co-Cr based PFM crowns have negative influences on periodontal tissue.The Ti PFM and all ceramic crown may affect periodontium less than the Co-Cr PFM in observation period of this study.