Distribution and drug resistance of Acinetobacter baumannii in nosocomial infections.

Objective To investigate the distribution and drug resistance of Acinetobacter baumannii in nosocomial infections to provide scientific evidence for the clinical use of antibiotics.Methods Drug sensitivity testing of A.baumannii isolated from clinical specimens was performed with a broth microdilution test and its drug resistance was analyzed.Results A total of 347 strains of A.baumannii were mainly isolated from sputum(about 67.4%) and mainly isolated from the intensive care unit(ICU) and departments of respiratory medicine,rehabilitation,and neurology.Testing A.baumannii sensitivity to 9 kinds of antibiotics indicated its sensitivity to imipenem(78.4%).A.baumannii sensitivity to ceftazidime,tobramycin,levofloxacin,cefepime,ciprofloxacin,trimethoprim/sulfamethoxazole,and gentamicin was about 30%-41%.Its sensitivity to ampicillin was only 6%.The sensitivity of A.baumannii to 9 kinds of antibiotics has tended to decrease.Conclusion Drug resistance of A.baumannii is a very serious issue.Clinicians should use antibiotics rationally according to the results of drug susceptibility tests.