Drug resistance and distribution of 538 Acinetobacter baumanniiisolates

OBJECTIVE To investigate drug resistance and the distribution of Acinetobacter baumannii in recent years so as to provide basis for clinical treatment and control of nosocomial infections.METHODS A total of 538 stains of A.baumannii were collected from 2008 to 2010,the drug resistance rate and the distribution were analyzed retrospectively.RESULTS Totally 538 strains of A.baumannii were mainly isolated from sputum(76.2%);the drug resistance rates of A.baumannii to cefoperazone/sulbactam,imipenem,meropenem,amikacin,piperacillin/tazobactam,cefepime,levofloxacin,ceftazidime,ciprofloxacin,cidomycin,sulfamethoxazole/trimethoprim,piperacillin,and ceftriaxone were 29.2%,41.6%,44.8%,59.5%,63%,64.3%,65.6%,66.4%,69.5%,69.9%,73.0%,77.9%,and 80.9%,respectively,and the drug resistance of A.baumannii to 13 commonly used antibiotics has been increasing year by year.CONCLUSION We should pay attention to the dynamic monitoring of drug resistance of A.baumannii,and the antibiotics should be chosen according to drug susceptibility testing in the clinical practice so as to prevent the outbreak and prevalence of multidrug-resistant A.baumannii.